But in other chimeras, there is a dominant set of DNA in the body, with the other set only present in certain tissues. To obtain Sperm meets egg, and we get a zygote with a full set of chromosomes. Although the first case was described in 1962 [1], its incidence is still unknown. As a consequence, instead of having cells with identical DNA throughout their body, a chimera has different DNA present in different parts of their body so that the DNA in their blood, for example, may not be the same as the DNA in their saliva. In fact, chimerism can be measured in the lab in order to track the progress of the engraftment and make sure that the cancerous blood cells are no longer detectable and have been replaced by healthy ones made by the graft. Tonights results are below! Orange cells indicate 46,XX, and green cells indicate 46,XY. - Cells that belong to the fetus can continue circulating in the mothers blood for years, and while they may decrease the mothers risk of cancer and increase her risk of autoimmune diseases, more studies are needed to clarify these associations. ), FJ - PUBLISHING - Last name of brothers James, John, Joseph & Fletcher, whose co. published magazines with their name as well as books. As Tindell surveyed the evidence against Fairchild, he discovered the article Disputed Maternity Leading to Identification of Tetragametic Chimerism, published on 16 May 2002 in The New England Journal of Medicine, in which doctor Neng Yu and a team of researchers presented the case of Karen Keegan, a woman who had needed a kidney transplant. Most organisms only have one set of DNA, which is present and identical in every cell throughout that organisms body. 17.86% in first on buzzer (10/56) The region showing four allele combinations, where the possible SNP genotypes were BBB, BBA, AAB, and AAA, were on chromosome X (Fig. When Fairchild applied for enforcement of child support in 2002, providing DNA evidence of Townsend's paternity was a routine requirement. According to a documentary produced on Fairchilds case, The Twin Inside Me, a social worker called Fairchild to come to her office after obtaining the maternity test results. FISH showed nuc ish XX[83]/XY[17]. International Journal of Legal Medicine Mixed fields with anti-B and anti-A+B antisera led to the conclusion that blood group B and 0 cell populations were present in a 1:1 ratio. Transfusion 46:19781981, Article 1. It seemed as if TPTB were trying to keep the streak going but DJ just took too long. There is more than one way of creating a chimera, however. A man accused of a crime while he was behind bars.
Tetragametic chimerism detected in a healthy woman with mixed-field DD3 - What is veterinarian? Correspondence to Epigenetics. The precise position of the external urethral opening was normal. 3 Laursen RJ, Alsbjerg B, Vogel I, Gravholt CH, Elbaek H, Lildballe DL, et al. 10. 1/1 in Final Jeopardy I didnt anticipate the issue with Mayim calling on R-G whilst R-G was calling out the answer, the two speaking simultaneously, and other issues. 17. He was the best!! Number of clues left unrevealed this season: 1 (0.05 per episode average), 0 Daily Doubles, Game Stats: I have no idea what youre talking about. (Click Here for Methodology), Ben Chan, career statistics: To confirm chimerism, we carried out SNP microarray analysis using a CytoScan 750K Array (Affymetrix, Santa Clara, CA). Genotyping of XX/XY chimeras is important not only for clarifying the pathogenesis of chimeras but also for understanding of the disease. J Med Genet. Average Coryat: $22,200, Brittany Iburg, career statistics: Jonathan $31,000 Coryat, 32 correct, 0 incorrect, 46.43% in first on buzzer (26/56), 5/5 on rebound attempts (on 7 rebound opportunities) 19. At first, the technical difficulties involved in finding these chimeras might have contributed to an underestimation, but given the large number of paternity tests and direct-to-consumer genetic tests regularly done, and the slow trickle of case reports in the scientific literature, its unlikely that vanishing twins are commonplace. The company became known on the book side for publishing works such as Moby-Dick, Ben-Hur, and many other books, and likely even better known for its 19th century magazines such as Harpers New Monthly Magazine, Harpers Weekly, and Harpers Bazaar. It may not be copied without linked attribution back to this page.). Internet Explorer). Mariko Taniguchi-Ikeda. Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis. 1). Tournament of Champions Tracker; Champions Archive; Past Tournaments; Leaderboard of Legends; Be on J! Robinson-Gissette -400 +2000 (Jonathan 17000 Brittany 4400) DD1 - $400 - & PLAYING TRIANGLE - The ancient Greeks compared the constellation Triangulum to this capital letter of theirs (Brittany doubled to $2,800. Whereas tetragametic chimeras are known as the most common subtype of XX/XY chimeras, which are derived from the simple fusion of two different zygotes, parthenogenetic chimeras and androgenetic chimeras [8, 11] undergo endoreplication of one of the gametic genomes. DD3 - What is veterinarian? The Jeopardy! TIL Ken Jennings and his friend Earl both passed the Jeopardy auditions together, but Earl couldn't compete until Ken lost as they weren't allowed to compete at the same time. The evidence they have is sperm, which famously contains DNA. Lach Trash: $7,200 (on 6 Triple Stumpers) Jeopardy! Combined Coryat Score: $38,800 and especially near any open wells. Different molecular studies have confirmed this mechanism ( Green et al. 4. The authors declare that they have no conflicts of interest. Once Fairchilds mother submitted her DNA in comparison, matching as the maternal grandmother of the children, the judge dismissed the case, admitting he was wrong. streak: 1.887 games. 19. With no other tell-tale manifestation of chimerism, Keegan had spent most of her life not knowing that she was probably the result of twins that had fused in early development. These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. Rather than sending Fairchild for a lie detector test, though, the prosecutors office sent her a court summons to determine Fairchilds relationship with her children. The patients toy preference was wheeled vehicles and superheroes. The season 4 finale of the television show C.S.I. 2018;35:34552. Clinical findings of the patient. 1/1 on Daily Doubles (Net Earned: $1,400) Posted By: Andy Saunders Tetragametic chimerism is assumed to be a rare condition; however, most cases are likely to remain unrecognized. She was a monstrous creature, a hybrid of many animals, ultimately slayed by the hero Bellerophon. The prosecutors office in the state of Washington took over Fairchilds case suspecting welfare fraud. By the time they taped the first show of the day it was 5pm, and we had shown up at about 10:30 am. It divides into two, making copies of these chromosomes, and we think that every cell down the line ends up with the same genetic bundle. Next, to confirm chimerism, we analyzed the B-allele frequency of autosomes and the X chromosome [13, 14]. Kaye acknowledges that human chimerism should be a consideration in DNA testing, given its unknown frequency, but rejects the statement that it is a significant obstacle to its use in forensic investigation. Thats when Keegan was told that she was not the mother of two of her three children. J Assist Reprod Genet. Bone Marrow Transplant 35:107119, Bolan CD, Leitman SF, Griffith LM et al (2001) Delayed donor red cell chimerism and pure red cell aplasia following major AB0-incompatible nonmyeloablative hematopoietic stem cell transplantation. Jonathan $30,000 2013;14:30720. However, with the new evidence that an infant Fairchild had undeniably delivered did not match her DNA, a lawyer, Alan Tindell, agreed to represent her. When wearing a mask, ensure that your mask covers both your nose and your mouth. 12. There was a lady with a couple kids going through a divorce and custody, etc. Please upgrade your browser to improve your experience. Fan Online Store! Jonathan dropped $7,500 to win with $22,500 for a two-day total of $51,700. pointed that out in a somewhat flamboyant fashion by having its criminal proclaim that, Im a creature of myth. He was a chimera, though not the sort with a fire-breathing head. 8. Macro- and microscopically, the patient had ambiguous external genitalia, male-type internal genitalia (epididymis), and bilateral testes (Fig. DNA analysis of tissues revealed a tetragametic chimerism due to an apparent double parental contribution of nuclei in a phenotypically normal man. 2b, c. b Top, diagram of XX and XY chimeric ratios of three tissues from the patient. Thank you. 13. Its part of why Matts strategy (and execution) was so successful. Please welcome today's contestants: Robinson-Gissette, an art assistant, has tetragametic chimerism;Brittany, a stay-at-home mom, backpacked along the bottom of the Grand Canyon; andJonathan, an actor, sang in cathedrals all over the world. 11. Come to think of it, I might just go by R-G on Jeopardy! When the marrow recipient was arrested, his blood was collected and its DNA was entered into the database, where it proved a match during the sexual assault case. 1) & PLAYING TRIANGLE $400 (clue #17) Robinson-Gissette, an art assistant, has tetragametic chimerism; Brittany, a stay-at-home mom, backpacked along the bottom of the Grand Canyon; and. She was pregnant with her third child when she and the father of her children, Jamie Townsend, separated. Tetragametic chimerism appears to be rare. The vanishing twins, like Karen Keegan and Lydia Fairchild, came about from the fusion of distinct zygotes. These allele combinations were detected throughout the whole genome (Supplementary Fig. Keegans family members, including her husband and two of her three sons, submitted DNA to see if they would be a match to donate a kidney to her. 13. However, once they took a sample from Fairchilds cervix, the narrow tube that connects the vagina to the uterus, they finally found a second DNA lineage that matched those of her children.
If you are going to quote any information from this page or this website, attribution is required. Endoduplication of the maternal genome occurs just before fertilization with two spermatozoa. J! They also found that, although the DNA in Fairchild's skin and hair did not match her children's, the DNA from a cervical smear test did match. After two weeks, the court received results that there was no genetic match between Fairchild and her infant. I wish him well! The XY/XX ratio in buccal cells (17%) was lower than that in peripheral blood cells (87%). 3. Malan V, Vekemans M, Turleau C. Chimera and other fertilization errors. Avg. Scan this QR code to download the app now. (2016, identifying 36 SNPs shared with the SNP array chip.Both NGS data from the blood and the skin DNA samples were collected thus determining the genotypic layout in both tissues. So, the woman also happened to be pregnant at the time, so the court ordered a witness to present at the birth, and to take an immediate blood sample of the child. Brittany $5,200 + $2,001 = $7,201 (What is Harper?) A negative anamnesis for both transplantation and transfusion suggested a chimerism. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. Have you had a chance to listen to our podcast game show, Todays Final Jeopardy Monday, May 1, 2023, Todays Final Jeopardy Friday, April 28, 2023, Todays Final Jeopardy Thursday, April 27, 2023, Todays Final Jeopardy Wednesday, April 26, 2023, Todays Final Jeopardy Tuesday, April 25, 2023. 3/4 on Daily Doubles (Net Earned: $3,600) DNA may not lie, but we have to understand its rare eccentricities. From the point of view of genetic counseling, the recurrence risk of this condition in this family is low because of the lack of a family history. Arthur Chu $397,200 Jeopardata; This Week on Jeopardy! In human reproduction, one sperm typically fuses with one egg to create a fertilized egg that can develop into a fetus.
051602 Disputed Maternity Leading to Identification of Counts of Target Development Levels for diseases known to be associated with this disease. To investigate the parental origin of the genome in the patient, we performed microsatellite marker analysis, as known as short tandem repeat (STR) analysis. Blood 91:16871694, Article 10 correct, 7 incorrect James and John Harper, printers, founded J & J Harper in New York City in 1817. Tetragametic chimeras can have what doctors refer to as atypical genital appearance, although not all intersex people are chimeras, and not all chimeras are intersex. If they attack the recipients cells, doctors call this graft-versus-host disease.. Ken Jennings $2,520,700 Kaye states that Krimsky and Simoncellis point that any human could display some trait of chimerism is only true because there are numerous ways someone could be considered a chimera. ", Bortolus, Renata, Fabio Parazzini, Liliane Chatenoud, Guido Benzi, Massimiliano Maria Bianchi, and Alberto Marini. Google Scholar. c The ultrasound echoic level of both gonads was homogeneous. This indicates the presence of two different genomes, demonstrating that the patient does not show mosaicism but is an XX/XY chimera. Therefore, we determined the dispermic origin of the chimera. Jason Zuffranieri $542,496 Correct Qs: DD1 - What is delta? Click "Explore Associated Targets" to view more facets and details for the target list. You are using an outdated browser. . In fact, when tetragametic chimeras have no idea that they are creatures of myth, to put it theatrically, it can make for puzzling discoveries and leave some in legal trouble. Scientists ended up testing all manners of biological specimens from herher hair, her skin, cells from inside her mouth, even tissue that had been removed from her in the past and preservedand they found in some of these two different DNA profiles. Each time, the results indicated that Fairchild was not the biological mother of the two children. 1/1 on Daily Doubles (Net Earned: $2,000) Although she was able to produce photographs of her with her children throughout their lives, the prosecutors office continued to allege that she was not being truthful about the origin of her pregnancies, and that because she had claimed her children as dependents on her application for benefits, doing so constituted welfare fraud. Article Cris Pannullo $748,286 It was while investigating an illness in her early teens that Muhl discovered both her allergies and unusual birthmark were the result of tetragametic chimerism between her own fertilised egg and that of a fraternal twin. Such examples have been found in mice and other mammalian species including humans. Tetragametic chimerism, where a twin pregnancy evolves into one child, is currently believed to be one of the rarer forms. Arthur Chu $297,200 The Chimera was another famous creature in Greek mythology that had parts of various creatures: it had the head of a lion, the body of a goat, and the backside of a serpent. This subreddit is not affiliated with, sponsored by, or operated by Jeopardy Productions or Sony Pictures. Due to this statistic, it is quite possible that tetragametic chimerism is more common than current data implies. ISSN 1435-232X (online)
Brittany $4,400 ), DD2 - $2,000 - EUROPEAN HISTORY - Though Pippin III founded this Frankish dynasty in 751, its name comes from the many Charleses who ruled it (Robinson-Gissette won the table limit of $2,000. When Fairchild went to court, she represented herself, bringing photos from her two previous pregnancies and pictures of her with her children as infants. Although there had been a witness for the birth and blood samples, the judge maintained his statement that Fairchild was being deceitful about the pregnancies in some way. Malan V, Gesny R, Morichon-Delvallez N, Aubry MC, Benachi A, Sanlaville D, et al.
tetragametic chimerism jeopardy contestant J Assist Reprod Genet. 2. 1), suggesting that the chimera is possibly tetragenic, parthenogenic or androgenic. Women told they are not the mothers of children they gave birth to.
The Impossible Crime (Unless You Know About Chimeras) The court suggested placing her two children in separate foster homes while the case was contested to monitor the childrens wellbeing, since officials assumed that Fairchild was being fraudulent about her relationship with the children. Haplotype sharing region encompasses 1.5Gbps, which is approximately half of the entire genome (Supplementary Fig. 14. Fairchild matched that pattern, having one set of DNA throughout most of the cells in her body, and another distinct set of DNA in her cervical tissue. If Keegan had been a chimera, might Fairchild not be one too? Russ Schumacher $344,800 2. More information about Final Jeopardy: (The following write-up is original content and is copyright 2021 The Jeopardy! Jonathan $30,000 $7,500 = $22,500 (What is Penguin?) A genomic view of mosaicism and human disease. Mixed fields with anti-B and anti-A+B antisera led to the conclusion that blood group B and 0 cell populations were present in a 1:1 ratio. However, SNP array is not able to classify chimerism. 7: 18.230% ), DD3 - $2,000 - EDUCATION FIRSTS - In 1761 Claude Bourgelat, who wrote "Sur la Mdecine des Chevaux", set up the first school for this profession (On the last clue of DJ, Jonathan won $1,000 from his score of $29,000 vs. $5,200 for Brittany. Correct Qs: DD1 - What is delta? The second type is called tetragametic chimerism. Prosecutors called for her two children to be taken away from her, believing them not to be hers. Study design and methods: Blood grouping was performed with standard gel centrifugation test cards, ABO genotyping by sequence-specific primers (SSPs) and . Article The Fairchild case of chimerism prompted many questions about the reliance on DNA evidence in the US justice system and how common chimerism might be in the general population. Hum Reprod 21:579591, Drexler C, Glock B, Vadon M et al (2005) Tetragametic chimerism detected in a healthy woman with mixed-field agglutination reactions in AB0 blood grouping. When twins are growing in the womb, the blood vessels feeding them can connect. Robinson-Gissette $3,600 $3,600 = $0 (What is Pilii (Pulitzer))
Chimera (genetics) - Wikipedia All markers showed the contribution of two paternal alleles and one maternal allele in the chimera (Fig. A tetragametic chimera thus has two main types of cells making up their body. (Although their deliberate choice of clues on those occasions when they did get a correct response likely also contributed). SNP array and STR analysis. All this talk of genetic anomalies and quirks brings us right back to Alaska. 2021-05-20T21:33:12-08:00 . Fairchild appeared in court on a Friday. The use of DNA in courts relies on the belief that there is a direct connection between a DNA sample and the person it is taken from. 1. He just was not able to recover and the second-longest winning streak in the history of the show came to an end. Nobody anywhere else on the Internet has brought this up, either. James Holzhauer $2,962,216 The company merged with Row, Peterson & Company to become Harper & Row in 1962, and, after a purchase by NewsCorp in 1987, merged with William Collins, Sons in 1990 to become HarperCollins. Coryat lost to incorrect responses (less double-correct responses): $6,800, Jonathan Fisher, career statistics: 9. 2007;22:103741. Fairchild stood accused of fraud by either claiming benefits for other people's children, or taking part in a surrogacy scam, and records of her prior births were put similarly in doubt. Ryan Long $299,400 /r/Jeopardy, a subreddit for the appreciation of The World's Greatest Game Show: JEOPARDY! They asserted she was committing welfare fraud by lying about her relationship with her children. 17. A case of chimerism-induced paternity confusion: what ART practitioners can do to prevent future calamity for families.
Chimerism and tetragametic chimerism in humans: implications - PubMed However, as the chimeric ratio in this patient is different among various tissues in the body [15], androgen or estrogen exposure to the entire body cannot be assessed and it is difficult to predict the risk of problems, such as gonadoblastoma (Fig. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Since Jeopardy only keeps auditions until the end of the season, Earl didn't get a chance to play due to Ken's long streak Take-home message: d Testis biopsy of the patient (left). that had tetragametic chimerism . 9. Today ends a 23-game streak where we saw all 61 clues; the longest since 2002. We thank Prof. Mario Sessarego for the cytogenetic analysis. In the documentary, Townsend, the father of the three children, states that if the third infant had not exhibited the same contradictory DNA results, he believes that the couple would have lost their children permanently. Mattea Roach $570,983 It is known as microchimerism: fetal microchimerism refers to the presence of fetal cells in the mother and maternal microchimerism, to the presence of the mothers cells in the fetus. It was a swab of his cheeksand the fact that he physically could not have committed the crimethat exonerated him. Brad Rutter $4,953,436 0/1 on Daily Doubles (Net Earned: -$1,000) Proc Natl Acad Sci USA. The documentary The Twin Inside Me, which first aired in 2006, documents a firsthand account from Fairchild and her family. Part of Springer Nature. Where chimerism involves contrasting sex . Google Scholar, Dini G, Floris R, Garaventa A et al (2000) Long-term follow-up of two children with a variant of mild autosomal recessive osteopetrosis undergoing bone marrow transplantation. Fairchild was carrying two different sets of DNA (with one of them of being her unborn twin's), the defining characteristic of chimerism. He was a genetic chimera. From the blood alone, these two brothers were now identical twins. When an organism has cells with different genetic codes but they all come from a single zygote, that is called mosaicism. Jonathan, an actor, sang in cathedrals all over the world. 2006;43:24854. We concluded that the patient is a parthenogenetic chimera, which is composed of two paternal alleles and one duplicated maternal allele (Fig. Walsh correctly answered "It" (by author Stephen King), ending the show with $18,800 for a four-day total win of $81,700. N Engl J Med. 23. We used genomic DNA, which was isolated from nail as a template for microarray analysis. Yes, the winner of the previous game usually DOES have an edge at the beginning of a game due to less nerves than the 2 new contestants. Robinson-Gissette $400, Daily Double locations: Int J Legal Med 122:353356, Boklage CE (2006) Embryogenesis of chimeras, twins and anterior midline asymmetries. [2][3] He realized that Fairchild's case might also be caused by chimerism. When Fairchild applied for enforcement of child support in 2002, providing DNA evidence of Townsend . Round: IN- IS OUT $1200 We first determined the patients genotype as well as the genotype of the parents. During that visit, the social worker and a legal representative confronted Fairchild with DNA evidence that her children were not biologically related to her. "Chimeras: double the DNA-double the fun for crime scene investigators, prosecutors, and defense attorneys. Sheets KM, Baird ML, Heinig J, Davis D, Sabatini M, Starr DB. ), DD3 - $2,000 - EDUCATION FIRSTS - In 1761 Claude Bourgelat, who wrote "Sur la Mdecine des Chevaux", set up the first school for this profession (On the last clue of DJ, Jonathan won $1,000 from his score of $29,000 vs. $5,200 for Brittany. So they sent the woman for various tissue sampling and finally found a match. Joseph and Fletcher joined the company in the 1820s and the company was renamed Harper & Brothers in 1833. Kaye also asserts that chimerism in the cases of Fairchild and Keegan are the exception and should not change how the public views DNA evidence. "Human Chimeras That Already Exist.". The rare condition can happen during fetal . Those researchers then tested Keegans third son, who had not originally been tested because he was a child at the time and would be unable to donate a kidney. FJ - What is Harper? Verdiani, S., Bonsignore, A., Casarino, L. et al. Conlin LK, Thiel BD, Bonnemann CG, Medne L, Ernst LM, Zackai EH, et al. October 12, 2021. Giurgea I, Sanlaville D, Fournet JC, Sempoux C, Bellann-Chantelot C, Touati G, et al. Chimera resulting from the fusion of XX- and XY-embryos are the most likely to be discovered because mixed gonads can result in abnormalities of the external genitalia. Mattea Roach $560,983 7: 24.987% Abstract. Larissa Kelly $660,930 The yellow and pink colored chromosomes are of maternal origin. 22. 5: 36.014% The woman, singer Taylor Muhl, has a condition called chimerism, meaning she has two sets of DNA, each with the genetic code to make a separate person. Some cells come from sperm 1 and egg 1, while the rest come from sperm 2 and egg 2. tetragametic chimerism jeopardy contestant. 4. Triple Stumper of the day: If the players focused on the last six words of this lengthy clue, they likely would have known that "the short route between 2 points" is a straight line. 15. Scan data were visualized using ChAS 3.2 software (Affymetrix). tetragametic chimerism occurs through the fertil-ization of two ova by two spermatozoa, followed by the fusion of the zygotes and the development of an organism with intermingled cell lines. recap for Tue., Oct. 12 Please welcome today's contestants: - Robinson-Gissette, an art assistant, has tetragametic chimerism; - Brittany, a stay-at-home mom, backpacked along the bottom of the Grand Canyon; and - Jonathan, an actor, sang in cathedrals all over the world. https://doi.org/10.1038/s10038-020-0748-4, DOI: https://doi.org/10.1038/s10038-020-0748-4. However, Kaye states that those forms of chimerism would not affect how DNA is left in crime scenes. Alex Jacob $424,802 tetragametic chimerism jeopardy contestant. Sex-chromosome discordant chimerism (XX/XY chimerism) is a rare chromosomal disorder in humans. Overall Daily Double Efficiency for this game: 203, Unplayed clues: J!6; J!6 Alexa; Infinite Final J! Check out my new Betting Strategy 101 page, Did you know that you can now find game-by-game stats of everyone, now including Jason Zuffranieri and James Holzhauer, who has won 10 or more games on.
Jeopardy! recap for Tue., Oct. 12 - The Avocado , 1998 ; Yu et al . 1/2 on rebound attempts (on 6 rebound opportunities) You will noticed all three contestants do in fact get much more into the game after the first break. Finally, a lawyer did take her on as a client and stumbled upon the Keegan case as reported in the New England Journal of Medicine. Provided by the Springer Nature SharedIt content-sharing initiative, Over 10 million scientific documents at your fingertips, Not logged in Fairchild states she could not convince a lawyer to represent her because they told her they would not win a case against DNA evidence. 8. 3) EDUCATION FIRSTS $2000 (clue #29, $1200 left on board) The XX/XY chimera manifests variable genital phenotypes, ranging from normal male or female genitalia to different degrees of ambiguous genitalia. However, sometimes the ovaries, which are organs in the female body that produce and store eggs, release more than one egg at a time, a phenomenon known as hyperovulation. DJ! Two weeks later, DNA tests seemed to indicate that she was also not the mother of that child. In 1969, three researchers from the University of California, San Francisco, collected white blood cells from women pregnant with boys and found that some had what appeared to be a Y chromosome. Clin Genet. While some high-profile cases have made headlines, typically, this condition has no symptoms. Schematic drawing of how a parthenogenetic chimera is produced.
citibank check ops bank by mail san antonio Ken Jennings $4,370,700 I was sitting in the room when Abirami Chidambaram, then of the Alaska State Scientific Crime Detection Laboratory, presented this fascinating case at a genetics conference in Salt Lake City in 2005.